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Anti-RAVER1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Ribonucleoprotein, PTB-binding 1 (also known as RAVER1), is a human gene. Enables RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm. Predicted to be active in nucleus.

Synonyms

B-cell differentiation antigen CD72; Lyb-2; CD72; CD72

Gene Name

RAVER1

Gene ID

125950

UniProt

Q8IY67

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RAVER1 recombinant protein (Position: D209-H567) .

Clonality

Polyclonal

Tissue Specificity

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells

Purification

Immunogen affinity purified.

Form

Liquid

Function

Plays a role in B-cell proliferation and differentiation.

References & Citations

1. Gromak, N., Rideau, A., Southby, J., Scadden, A. D. J., Gooding, C., Huttelmaier, S., Singer, R. H., Smith, C. W. J. The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing. EMBO J. 22: 6356-6364, 2003. 2. Huttelmaier, S., Illenberger, S., Grosheva, I., Rudiger, M., Singer, R. H., Jockusch, B. M. Raver1, a dual compartment protein, is a ligand for PTB/hnRNP1 and microfilament attachment proteins. J. Cell Biol. 155: 775-785, 2001. 3. Nagase, T., Kikuno, R., Ohara, O. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. DNA Res. 8: 319-327, 2001.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

CD72 molecule

Subcellular Location

Membrane; Single-pass type II membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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