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Anti-C18orf22/RBFA Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Predicted to be involved in rRNA processing. Predicted to be located in mitochondrion.

Synonyms

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

Gene Name

RBFA

Gene ID

79863

UniProt

Q8N0V3

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human C18orf22/RBFA recombinant protein (Position: L15-D319) .

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Applications

Flow Cytometry

Field of Research

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Form

Liquid

Function

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

References & Citations

1. Kuwasako, K. , Suzuki, S. , Nameki, N. , Takizawa, M. , Takahashi, M. , & Tsuda, K. , et al. (2022) . 1h, 13c, and 15n resonance assignments and solution structures of the kh domain of human ribosome binding factor a, mtrbfa, involved in mitochondrial ribosome biogenesis. Biomolecular NMR Assignments, 1-7. 2. Rozanska, A. , Richter-Dennerlein, R. , Rorbach, J. , Gao, F. , & Lightowlers, R. N. . (2017) . The human rna-binding protein rbfa promotes the maturation of the mitochondrial ribosome. Biochemical Journal, 474 (13), 2145-2158. 3. Hauri, S. , Wepf, A. , Drogen, A. V. , Varjosalo, M. , & Gstaiger, M. . (2013) . Interaction proteome of human hippo signaling: modular control of the co-activator yap1. Molecular Systems Biology, 9 (1), 713.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64099 MW

Applications Notes

6

Gene Name Synonym

RNA-binding protein 47

Subcellular Location

Nucleus .

Protein Name

Follicular dendritic cell secreted peptide

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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