Anti-RAI14 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Ankycorbin is a protein that in humans is encoded by the RAI14 gene. Predicted to enable actin binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of NIK/NF-kappaB signaling; and spermatogenesis. Located in cytosol; fibrillar center; and nucleoplasm.
Synonyms
Tudor domain-containing protein 3; TDRD3
Gene Name
RAI14
Gene ID
26064
UniProt
Q9P0K7
Host
Rabbit
Reactivity
Human, Mouse
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human RAI14 recombinant protein (Position: G53-E680) .
Clonality
Polyclonal
Tissue Specificity
Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Applications
Flow Cytometry
Field of Research
Adaptive Immunity, B Cells, Immunoglobulins, Immunology
Purification
Immunogen affinity purified.
Form
Liquid
Function
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.
References & Citations
1. Kutty, R. K., Kutty, G., Samuel, W., Duncan, T., Bridges, C. C., El-Sherbeeny, A., Nagineni, C. N., Smith, S. B., Wiggert, B. Molecular characterization and developmental expression of NORPEG, a novel gene induced by retinoic acid. J. Biol. Chem. 276: 2831-2840, 2001. 2. Nagase, T., Kikuno, R., Ishikawa, K., Hirosawa, M., Ohara, O. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 7: 65-73, 2000.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Tudor domain containing 3
Subcellular Location
Nucleus. Cytoplasm.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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