Anti-RBMS1 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
RNA-binding motif, single-stranded-interacting protein 1 is a protein that in humans is encoded by the RBMS1 gene. This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12.
Synonyms
Transcription factor Sp6; Krueppel-like factor 14; SP6; KLF14
Gene Name
RBMS1
Gene ID
5937
UniProt
P29558
Host
Rabbit
Reactivity
Human, Mouse
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human RBMS1 recombinant protein (Position: K3-K406) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
Flow Cytometry
Field of Research
Cancer, Cell Biology, Cell Cycle, Cell Division, Cell Type Marker, Cell Type Markers, Neurogenesis, Neurology Process, Neuron Marker, Neuroscience, Tags & Cell Markers, Tumor Biomarkers
Purification
Immunogen affinity purified.
Form
Liquid
Function
Promotes cell proliferation.
References & Citations
1. Gross, M. B. Personal Communication. Baltimore, Md. 3/24/2016. 2. Haigermoser, C., Fujimoto, M., Iguchi-Ariga, S. M. M., Ariga, H. Cloning and characterization of the genomic DNA of the human MSSP genes. Nucleic Acids Res. 24: 3846-3857, 1996. 3. Hubberten, M., Bochenek, G., Chen, H., Hasler, R., Wiehe, R., Rosenstiel, P., Jepsen, S., Dommisch, H., Schaefer, A. S. Linear isoforms of the long noncoding RNA CDKN2B-AS1 regulate the c-myc-enhancer binding factor RBMS1. Europ. J. Hum. Genet. 27: 80-89, 2019.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Sp6 transcription factor
Subcellular Location
Nucleus.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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