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Anti-RBMS1 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

RNA-binding motif, single-stranded-interacting protein 1 is a protein that in humans is encoded by the RBMS1 gene. This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12.

Synonyms

Transcription factor Sp6; Krueppel-like factor 14; SP6; KLF14

Gene Name

RBMS1

Gene ID

5937

UniProt

P29558

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RBMS1 recombinant protein (Position: K3-K406) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

Flow Cytometry

Field of Research

Cancer, Cell Biology, Cell Cycle, Cell Division, Cell Type Marker, Cell Type Markers, Neurogenesis, Neurology Process, Neuron Marker, Neuroscience, Tags & Cell Markers, Tumor Biomarkers

Purification

Immunogen affinity purified.

Form

Liquid

Function

Promotes cell proliferation.

References & Citations

1. Gross, M. B. Personal Communication. Baltimore, Md. 3/24/2016. 2. Haigermoser, C., Fujimoto, M., Iguchi-Ariga, S. M. M., Ariga, H. Cloning and characterization of the genomic DNA of the human MSSP genes. Nucleic Acids Res. 24: 3846-3857, 1996. 3. Hubberten, M., Bochenek, G., Chen, H., Hasler, R., Wiehe, R., Rosenstiel, P., Jepsen, S., Dommisch, H., Schaefer, A. S. Linear isoforms of the long noncoding RNA CDKN2B-AS1 regulate the c-myc-enhancer binding factor RBMS1. Europ. J. Hum. Genet. 27: 80-89, 2019.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Sp6 transcription factor

Subcellular Location

Nucleus.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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