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Anti-SPOCK3 Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene

Synonyms

B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD272; BTLA

Gene Name

SPOCK3

Gene ID

50859

UniProt

Q9BQ16

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SPOCK3 recombinant protein (Position: Q104-H396) .

Clonality

Polyclonal

Tissue Specificity

Wide tissue distribution (highest in the pancreas and very low in brain) . Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, Immunology, T Cells

Purification

Immunogen affinity purified.

Form

Liquid

Function

Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.

References & Citations

1. Nakada, M., Yamada, A., Takino, T., Miyamori, H., Takahashi, T., Yamashita, J., Sato, H. Suppression of membrane-type 1 matrix metalloproteinase (MMP) -mediated MMP-2 activation and tumor invasion by testican 3 and its splicing variant gene product, N-Tes. Cancer Res. 61: 8896-8902, 2001. 2. Vannahme, C., Schubel, S., Herud, M., Gosling, S., Hulsmann, H., Paulsson, M., Hartmann, U., Maurer, P. Molecular cloning of testican-2: defining a novel calcium-binding proteoglycan family expressed in brain. J. Neurochem. 73: 12-20, 1999.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03151-1-Fluoro550

Calculated Molecular Weight

65411 MW

Applications Notes

6

Gene Name Synonym

B and T lymphocyte associated

Subcellular Location

Membrane.

Protein Name

Glutamate decarboxylase 2

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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