Anti-SPOCK3 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene
Synonyms
B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD272; BTLA
Gene Name
SPOCK3
Gene ID
50859
UniProt
Q9BQ16
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human SPOCK3 recombinant protein (Position: Q104-H396) .
Clonality
Polyclonal
Tissue Specificity
Wide tissue distribution (highest in the pancreas and very low in brain) . Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.
Applications
Flow Cytometry
Field of Research
Adaptive Immunity, Immunology, T Cells
Purification
Immunogen affinity purified.
Form
Liquid
Function
Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.
References & Citations
1. Nakada, M., Yamada, A., Takino, T., Miyamori, H., Takahashi, T., Yamashita, J., Sato, H. Suppression of membrane-type 1 matrix metalloproteinase (MMP) -mediated MMP-2 activation and tumor invasion by testican 3 and its splicing variant gene product, N-Tes. Cancer Res. 61: 8896-8902, 2001. 2. Vannahme, C., Schubel, S., Herud, M., Gosling, S., Hulsmann, H., Paulsson, M., Hartmann, U., Maurer, P. Molecular cloning of testican-2: defining a novel calcium-binding proteoglycan family expressed in brain. J. Neurochem. 73: 12-20, 1999.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
65411 MW
Applications Notes
6
Gene Name Synonym
B and T lymphocyte associated
Subcellular Location
Membrane.
Protein Name
Glutamate decarboxylase 2
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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