Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-WDR36 Antibody Picoband®

Boster Bio Anti-WDR36 Antibody Picoband® catalog # A05779-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

WD repeat-containing protein 36 is a protein that in humans is encoded by the WDR36 gene. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG) .

Synonyms

Protein phosphatase 1 regulatory subunit 14A;17 kDa PKC-potentiated inhibitory protein of PP1; Protein kinase C-potentiated inhibitor protein of 17 kDa; CPI-17; PPP1R14A; CPI17, PPP1INL

Gene Name

WDR36

Gene ID

134430

UniProt

Q8NI36

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human WDR36 recombinant protein (Position: R74-D865) .

Clonality

Polyclonal

Tissue Specificity

Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. .

Applications

WB, ICC, IF, Flow Cytometry, ELISA

Field of Research

Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.

References & Citations

1. Bernstein, K. A., Gallagher, J. E. G., Mitchell, B. M., Granneman, S., Baserga, S. J. The small-subunit processome is a ribosome assembly intermediate. Eukaryotic Cell 3: 1619-1626, 2004. 2. Fingert, J. H., Alward, W. L. M., Kwon, Y. H., Shankar, S. P., Andorf, J. L., Mackey, D. A., Sheffield, V. C., Stone, E. M. No association between variations in the WDR36 gene and primary open-angle glaucoma. Arch. Ophthal. 125: 434-436, 2007. 3. Footz, T. K., Johnson, J. L., Dubois, S., Boivin, N., Raymond, V., Walter, M. A. Glaucoma-associated WDR36 variants encode functional defects in a yeast model system. Hum. Molec. Genet. 18: 1276-1287, 2009.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

16693 MW

Observed Molecular Weight

105 kDa

Applications Notes

6

Gene Name Synonym

Protein phosphatase 1 regulatory subunit 14A

Subcellular Location

Cytoplasm .

Protein Name

Protein phosphatase 1 regulatory subunit 14A

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CU-T12-9
MF-0032646-01 1 mg

CU-T12-9

Ask
View Details
CU-T12-9
MF-0032646-02 5 mg

CU-T12-9

Ask
View Details
CU-T12-9
MF-0032646-03 1 mL - 10 mM (in DMSO)

CU-T12-9

Ask
View Details
CU-T12-9
MF-0032646-04 10 mg

CU-T12-9

Ask
View Details
CU-T12-9
MF-0032646-05 25 mg

CU-T12-9

Ask
View Details
CU-T12-9
MF-0032646-06 50 mg

CU-T12-9

Ask
View Details