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Anti-SUSD6 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

May play a role in growth-suppressive activity and cell death. May be involved in the production of chemokine molecules in umbilical vein endothelial cells (HUVECs) cultured in THP1 monocyte LPS-induced medium. Plays a role in preventing tumor onset.

Synonyms

DAP3-binding cell death enhancer 1; Death ligand signal enhancer; DELE1; DELE; KIAA0141

Gene Name

SUSD6

Gene ID

9766

UniProt

Q92537

Host

Rabbit

Reactivity

Human, Monkey

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SUSD6 recombinant protein (Position: L44-A303) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

Flow Cytometry

Field of Research

Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation.

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 1/15/2016. 2. Nagase, T., Seki, N., Ishikawa, K., Ohira, M., Kawarabayasi, Y., Ohara, O., Tanaka, A., Kotani, H., Miyajima, N., Nomura, N. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. DNA Res. 3: 321-329, 1996. 3. Polato, F., Rusconi, P., Zangrossi, S., Morelli, F., Boeri, M., Musi, A., Marchini, S., Castiglioni, V., Scanziani, E., Torri, V., Broggini, M. DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosuppressor. J. Nat. Cancer Inst. 106: dju053, 2014. Note: Electronic Article. Erratum: J. Nat. Cancer Inst. 106: dju199, 2014.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64099 MW

Applications Notes

6

Gene Name Synonym

DAP3 binding cell death enhancer 1

Subcellular Location

Mitochondrion.

Protein Name

DAP3 binding cell death enhancer 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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