Anti-Syntaxin 18/STX18 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
This gene encodes a member of the syntaxin family of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) which is part of a membrane tethering complex that includes other SNAREs and several peripheral membrane proteins, and is involved in vesicular transport between the endoplasmic reticulum (ER) and the Golgi complex. The encoded protein is important for the organization of the smooth, rough, and exit site ER subdomains. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants.
Synonyms
Solute carrier family 2, facilitated glucose transporter member 6; Glucose transporter type 6; GLUT-6; Glucose transporter type 9; GLUT-9; SLC2A6; GLUT9
Gene Name
STX18
Gene ID
53407
UniProt
Q9P2W9
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human Syntaxin 18/STX18 recombinant protein (Position: M1-R313) .
Clonality
Polyclonal
Tissue Specificity
Highly expressed in brain, spleen and peripheral blood leukocytes.
Applications
Flow Cytometry
Field of Research
Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction
Purification
Immunogen affinity purified.
Form
Liquid
Function
Facilitative glucose transporter; binds cytochalasin B with low affinity.
References & Citations
1. Hatsuzawa, K., Hirose, H., Tani, K., Yamamoto, A., Scheller, R. H., Tagaya, M. Syntaxin 18, a SNAP receptor that functions in the endoplasmic reticulum, intermediate compartment, and cis-Golgi vesicle trafficking. J. Biol. Chem. 275: 13713-13720, 2000.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Solute carrier family 2 member 6
Subcellular Location
Cell membrane. Multi-pass membrane protein.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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