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Anti-Syntaxin 6/STX6 Antibody Picoband®

Boster Bio Anti-Syntaxin 6/STX6 Antibody Picoband® catalog # A06586-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Syntaxin-6 is a protein that in humans is encoded by the STX6 gene. Enables syntaxin binding activity. Involved in several processes, including Golgi ribbon formation; retrograde transport, endosome to Golgi; and vesicle fusion. Acts upstream of or within endocytic recycling. Located in several cellular components, including early endosome; perinuclear region of cytoplasm; and trans-Golgi network. Part of SNARE complex.

Synonyms

Semaphorin-3B; Sema A (V) ; Semaphorin-V; Sema V; SEMA3B; SEMA5; SEMAA

Gene Name

STX6

Gene ID

10228

UniProt

O43752

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Syntaxin 6/STX6 recombinant protein (Position: M1-A239) .

Clonality

Polyclonal

Tissue Specificity

Expressed abundantly but differentially in a variety of neural and nonneural tissues.

Applications

WB, Flow Cytometry, ELISA

Field of Research

Adapters, Coat Proteins, Cytoplasmic, Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.

References & Citations

1. Advani, R. J., Bae, H.-R., Bock, J. B., Chao, D. S., Doung, Y.-C., Prekeris, R., Yoo, J.-S., Scheller, R. H. Seven novel mammalian SNARE proteins localize to distinct membrane compartments. J. Biol. Chem. 273: 10317-10324, 1998. 2. Charest, A., Lane, K., McMahon, K., Housman, D. E. Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6. J. Biol. Chem. 276: 29456-29465, 2001. 3. Cheng, J., Cebotaru, V., Cebotaru, L., Guggino, W. B. Syntaxin 6 and CAL mediate the degradation of the cystic fibrosis transmembrane conductance regulator. Molec. Biol. Cell 21: 1178-1187, 2010.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

104553 MW

Observed Molecular Weight

29 kDa

Applications Notes

6

Gene Name Synonym

Semaphorin 3B

Subcellular Location

Endoplasmic reticulum. Secreted.

Protein Name

AP-2 complex subunit beta

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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