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Anti-SNX31 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in intracellular protein transport. Predicted to be located in cytoskeleton. Predicted to be part of protein-containing complex. Predicted to be active in early endosome.

Synonyms

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

Gene Name

SNX31

Gene ID

169166

UniProt

Q8N9S9

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human SNX31 recombinant protein (Position: M1-Q243) .

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Applications

Flow Cytometry

Field of Research

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Form

Liquid

Function

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

References & Citations

1. Stumpf, A. M. Personal Communication. Baltimore, Md. 04/15/2022. 2. Tseng, H.-Y., Thorausch, N., Ziegler, T., Meves, A., Fassler, R., Bottcher, R. T. Sorting nexin 31 binds multiple beta integrin cytoplasmic domains and regulates beta-1 integrin surface levels and stability. J. Molec. Biol. 426: 3180-3194, 2014. 3. Vieira, N., Deng, F.-M., Liang, F.-X., Liao, Y., Chang, J., Zhou, G., Zheng, W., Simon, J.-P., Ding, M., Wu, X.-R., Romih, R., Kreibich, G., Sun, T.-T. SNX31: a novel sorting nexin associated with the uroplakin-degrading multivesicular bodies in terminally differentiated urothelial cells. PLoS One 9: e99644, 2014.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64099 MW

Applications Notes

6

Gene Name Synonym

RNA-binding protein 47

Subcellular Location

Nucleus .

Protein Name

Follicular dendritic cell secreted peptide

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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