Anti-SNF2H/SMARCA5 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 is a protein that in humans is encoded by the SMARCA5 gene. The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein.
Synonyms
WAP four-disulfide core domain protein 2; Epididymal secretory protein 4; RE4; Wfdc2
Gene Name
SMARCA5
Gene ID
8467
UniProt
O60264
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human SNF2H/SMARCA5 recombinant protein (Position: A54-K735) .
Clonality
Polyclonal
Applications
Flow Cytometry
Field of Research
Cell Type Markers, Tags & Cell Markers, Tumor Associated
Purification
Immunogen affinity purified.
Form
Liquid
Function
Broad range protease inhibitor. .
References & Citations
1. Aalfs, J. D., Narlikar, G. J., Kingston, R. E. Functional differences between the human ATP-dependent nucleosome remodeling proteins BRG1 and SNF2H. J. Biol. Chem. 276: 34270-34278, 2001. 2. Aihara, T., Miyoshi, Y., Koyama, K., Suzuki, M., Takahashi, E., Monden, M., Nakamura, Y. Cloning and mapping of SMARCA5 encoding hSNF2H, a novel human homologue of Drosophila ISWI. Cytogenet. Cell Genet. 81: 191-193, 1998. 3. Barisic, D., Stadler, M. B., Iurlaro, M., Schubeler, D. Mammalian ISWI and SWI/SNF selectively mediate binding of distinct transcription factors. Nature 569: 136-140, 2019.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
WAP four-disulfide core domain 2
Subcellular Location
Secreted .
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items