Anti-SMAP1 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Stromal membrane-associated protein 1 is a protein that in humans is encoded by the SMAP1 gene. The protein encoded by this gene is similar to the mouse stromal membrane-associated protein-1. This similarity suggests that this human gene product is also a type II membrane glycoprotein involved in the erythropoietic stimulatory activity of stromal cells. Alternate splicing results in multiple transcript variants encoding different isoforms.
Synonyms
Interleukin-17B; IL-17B; Cytokine CX1; Cytokine-like protein ZCYTO7; Neuronal interleukin-17-related factor; Il17b; Nirf, Zcyto7
Gene Name
SMAP1
Gene ID
60682
UniProt
Q8IYB5
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human SMAP1 recombinant protein (Position: K126-Q416) .
Clonality
Polyclonal
Tissue Specificity
Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.
Applications
Flow Cytometry
Field of Research
Cytokines, Immunology, Innate Immunity, Interleukins
Purification
Immunogen affinity purified.
Form
Liquid
Function
Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. .
References & Citations
1. Kobayashi, N., Kon, S., Henmi, Y., Funaki, T., Satake, M., Tanabe, K. The Arf GTPase-activating protein SMAP1 promotes transferrin receptor endocytosis and interacts with SMAP2. Biochem. Biophys. Res. Commun. 453: 473-479, 2014. 2. Marcos, I., Borrego, S., Rodriguez de Cordoba, S., Galan, J. J., Antinolo, G. Cloning, characterization and chromosome mapping of the human SMAP1 gene. Gene 292: 167-171, 2002. 3. Sato, Y., Hong, H. N., Yanai, N., Obinata, M. Involvement of stromal membrane-associated protein (SMAP-1) in erythropoietic microenvironment. J. Biochem. 124: 209-216, 1998.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Interleukin 17B
Subcellular Location
Secreted.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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