Anti-FATP4/SLC27A4 Antibody Picoband® Fluoro647 Conjugated

Long-chain fatty acid transport protein 4 is a protein that in humans is encoded by the SLC27A4 gene. This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome.

Cell Biology, Cytokines, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, Interferons, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers, Ubiquitin E3 Enzymes

1. Esperon-Moldes, U. S., Ginarte, M., Santamarina, M., Rodriguez-Lage, B., Rodriguez-Pazos, L., Vega, A. Novel compound heterozygous FATP4 mutations caused ichthyosis prematurity syndrome in Spanish sisters. Acta Paediat. 108: 763-765, 2019. 2. Gertow, K., Bellanda, M., Eriksson, P., Boquist, S., Hamsten, A., Sunnerhagen, M., Fisher, R. M. Genetic and structural evaluation of fatty acid transport protein-4 in relation to markers of the insulin resistance syndrome. J. Clin. Endocr. Metab. 89: 392-399, 2004. 3. Hirsch, D., Stahl, A., Lodish, H. F. A family of fatty acid transporters conserved from mycobacterium to man. Proc. Nat. Acad. Sci. 95: 8625-8629, 1998.