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Anti-FATP3/SLC27A3 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Long-chain fatty acid transport protein 3 is a protein that in humans is encoded by the SLC27A3 gene. This gene belongs to a family of integral membrane proteins and encodes a protein that is involved in lipid metabolism. The increased expression of this gene in human neural stem cells derived from induced pluripotent stem cells suggests that it plays an important role in early brain development. Naturally occurring mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants.

Synonyms

Mitochondrial import inner membrane translocase subunit Tim17-A; Inner membrane preprotein translocase Tim17a; TIMM17A; MIMT17; TIM17; TIM17A; TIMM17

Gene Name

SLC27A3

Gene ID

11000

UniProt

Q5K4L6

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human FATP3/SLC27A3 recombinant protein (Position: L192-I683) .

Clonality

Polyclonal

Applications

Flow Cytometry

Field of Research

Cancer, Metabolism, Mitochondrial Metabolism, Organelle Proteins, Pathways and Processes, Protein Trafficking, Signal Transduction, Tumor Biomarkers

Purification

Immunogen affinity purified.

Form

Liquid

Function

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

References & Citations

1. Camacho, J. A., Rioseco-Camacho, N. The human and mouse SLC25A29 mitochondrial transporters rescue the deficient ornithine metabolism in fibroblasts of patients with the hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. Pediat. Res. 66: 35-41, 2009. 2. Sekoguchi, E., Sato, N., Yasui, A., Fukada, S., Nimura, Y., Aburatani, H., Ikeda, K., Matsuura, A. A novel mitochondrial carnitine-acylcarnitine translocase induced by partial hepatectomy and fasting. J. Biol. Chem. 278: 38796-38802, 2003.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Translocase of inner mitochondrial membrane 17A

Subcellular Location

Mitochondrion inner membrane, Multi-pass membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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