Anti-VMAT2/SLC18A2 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments.

Synonyms

Cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD131; Csf2rb; Aic2b; Csf2rb1; Il3rb1

Gene Name

SLC18A2

Gene ID

6571

UniProt

Q05940

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human VMAT2/SLC18A2 recombinant protein (Position: M1-D514) .

Clonality

Polyclonal

Tissue Specificity

Broadly expressed with higher expression in heart.

Applications

Flow Cytometry

Field of Research

Auditory System, Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Neurogenesis, Neurology Process, Neuroscience, Nuclear, Sensory System, Signaling Pathways, Stem Cells, Transcription

Purification

Immunogen affinity purified.

Form

Liquid

Function

High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.

References & Citations

1. Erickson, J. D., Eiden, L. E., Hoffman, B. J. Expression cloning of a reserpine-sensitive vesicular monoamine transporter. Proc. Nat. Acad. Sci. 89: 10993-10997, 1992. 2. Fon, E. A., Pothos, E. N., Sun, B.-C., Killeen, N., Sulzer, D., Edwards, R. H. Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. Neuron 19: 1271-1283, 1997. 3. Lin, Z., Walther, D., Yu, X.-Y., Li, S., Drgon, T., Uhl, G. R. SLC18A2 promoter haplotypes and identification of a novel protective factor against alcoholism. Hum. Molec. Genet. 14: 1393-1404, 2005.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

38160 MW

Applications Notes

Gene Name Synonym

Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)

Subcellular Location

Membrane. Single-pass type I membrane protein.

Protein Name

Cone-rod homeobox protein

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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Anti-VMAT2/SLC18A2 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Applications Notes

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

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