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Anti-VMAT2/SLC18A2 Antibody Picoband®

Boster Bio Anti-VMAT2/SLC18A2 Antibody Picoband® catalog # A02232-1. Tested in ELISA, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments.

Synonyms

Cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD131; Csf2rb; Aic2b; Csf2rb1; Il3rb1

Gene Name

SLC18A2

Gene ID

6571

UniProt

Q05940

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human VMAT2/SLC18A2 recombinant protein (Position: M1-D514) .

Clonality

Polyclonal

Tissue Specificity

Broadly expressed with higher expression in heart.

Applications

WB, ELISA

Field of Research

Auditory System, Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Neurogenesis, Neurology Process, Neuroscience, Nuclear, Sensory System, Signaling Pathways, Stem Cells, Transcription

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.

References & Citations

1. Erickson, J. D., Eiden, L. E., Hoffman, B. J. Expression cloning of a reserpine-sensitive vesicular monoamine transporter. Proc. Nat. Acad. Sci. 89: 10993-10997, 1992. 2. Fon, E. A., Pothos, E. N., Sun, B.-C., Killeen, N., Sulzer, D., Edwards, R. H. Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. Neuron 19: 1271-1283, 1997. 3. Lin, Z., Walther, D., Yu, X.-Y., Li, S., Drgon, T., Uhl, G. R. SLC18A2 promoter haplotypes and identification of a novel protective factor against alcoholism. Hum. Molec. Genet. 14: 1393-1404, 2005.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

38160 MW

Observed Molecular Weight

75 kDa

Gene Name Synonym

Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)

Subcellular Location

Membrane. Single-pass type I membrane protein.

Protein Name

Cone-rod homeobox protein

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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