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Anti-NaDC-1/SLC13A2 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Solute carrier family 13 member 2 is a protein that is encoded in humans by the SLC13A2 gene. The protein encoded by this gene is a sodium-coupled citrate transporter that is regulated by the chaperone activity of cyclophilin b. The encoded protein may play a role in the formation of kidney stones.

Synonyms

Protein SOX-15; Protein SOX-12; Protein SOX-20; SOX15; SOX12; SOX20; SOX26; SOX27

Gene Name

SLC13A2

Gene ID

9058

UniProt

Q13183

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human NaDC-1/SLC13A2 recombinant protein (Position: A152-M417) .

Clonality

Polyclonal

Tissue Specificity

Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

Applications

Flow Cytometry

Field of Research

Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

Immunogen affinity purified.

Form

Liquid

Function

Binds to the 5'-AACAAT-3' sequence.

References & Citations

1. Mann, S. S., Hart, T. C., Pettenati, M. J., von Kap-herr, C., Holmes, R. P. Assignment of the sodium-dependent dicarboxylate transporter gene (SLC13A2 alias NaDC-1) to human chromosome region 17p11.1-q11.1 by radiation hybrid mapping and fluorescence in situ hybridization. Cytogenet. Cell Genet. 84: 89-90, 1999. 2. Pajor, A. M. Molecular cloning and functional expression of a sodium-dicarboxylate cotransporter from human kidney. Am. J. Physiol. 270: F642-F648, 1996. 3. Rogina, B., Reenan, R. A., Nilsen, S. P., Helfand, S. L. Extended life-span conferred by cotransporter gene mutations in Drosophila. Science 290: 2137-2140, 2000.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

49229 MW

Applications Notes

6

Gene Name Synonym

SRY-box 15

Subcellular Location

Nucleus.

Protein Name

Chromaffin granule amine transporter

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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