Anti-SGO2 Antibody Picoband® Fluoro594 Conjugated
Product Specifications
Background
Predicted to be involved in homologous chromosome segregation; meiotic sister chromatid cohesion; and mitotic sister chromatid segregation. Predicted to act upstream of or within meiotic nuclear division; positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric; and protein localization. Located in chromosome, centromeric region and nuclear body. Part of mitotic cohesin complex.
Synonyms
Gap junction gamma-1 protein; Connexin-45; Cx45; Gap junction alpha-7 protein; GJC1; GJA7
Gene Name
SGO2
Gene ID
151246
UniProt
Q562F6
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SGO2 recombinant protein (Position: N660-E1011) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed.
Applications
Flow Cytometry
Field of Research
Cell Adhesion, Cytoskeleton/ECM, Signal Transduction
Purification
Immunogen affinity purified.
Form
Liquid
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
References & Citations
1. Hartz, P. A. Personal Communication. Baltimore, Md. 11/20/2008. 2. Hellmuth, S., Gomez-H, L., Pendas, A. M., Stemmann, O. Securin-independent regulation of separase by checkpoint-induced shugoshin-MAD2. Nature 580: 536-541, 2020. 3. Huang, H., Feng, J., Famulski, J., Rattner, J. B., Liu, S. T., Kao, G. D., Muschel, R., Chan, G. K. T., Yen, T. J. Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments. J. Cell Biol. 177: 413-424, 2007.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
45470 MW
Applications Notes
6
Gene Name Synonym
Gap junction gamma-1 protein
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein Name
Gap junction gamma-1 protein
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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