Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-SERAC1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Serine active site-containing protein 1, or Protein SERAC1 is a protein in humans that is encoded by the SERAC1 gene. The protein encoded by this gene is a phosphatidylglycerol remodeling protein found at the interface of mitochondria and endoplasmic reticula, where it mediates phospholipid exchange. The encoded protein plays a major role in mitochondrial function and intracellular cholesterol trafficking. Defects in this gene are a cause of 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (MEGDEL) . Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.

Synonyms

FERM domain-containing protein 6; Willin; FRMD6; C14orf31

Gene Name

SERAC1

Gene ID

84947

UniProt

Q96JX3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SERAC1 recombinant protein (Position: E97-H623) .

Clonality

Polyclonal

Tissue Specificity

Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.

Applications

Flow Cytometry

Field of Research

Growth Factors/Hormones, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 7/17/2012. 2. Lumish, H. S., Yang, Y., Xia, F., Wilson, A., Chung, W. K. The expanding MEGDEL phenotype: optic nerve atrophy, microcephaly, and myoclonic epilepsy in a child with SERAC1 mutations. JIMD Rep. 16: 75-79, 2014. 3. Maas, R. R., Iwanicka-Pronicka, K., Kalkan Ucar, S., Alhaddad, B., AlSayed, M., Al-Owain, M. A., Al-Zaidan, H. I., Balasubramaniam, S., Baric, I., Bubshait, D. K., Burlina, A., Christodoulou, J., and 46 others. Progressive deafness-dystonia due to SERAC1 mutations: a study of 67 cases. Ann. Neurol. 82: 1004-1015, 2017.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

FERM domain containing 6

Subcellular Location

Cell membrane. Peripheral membrane protein. Cytoplasmic side. Cytoplasm.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

STAT5B siRNA (Mouse)
MBS8211708-01 15 nmol

STAT5B siRNA (Mouse)

Ask
View Details
STAT5B siRNA (Mouse)
MBS8211708-02 30 nmol

STAT5B siRNA (Mouse)

Ask
View Details
STAT5B siRNA (Mouse)
MBS8211708-03 5x 30 nmol

STAT5B siRNA (Mouse)

Ask
View Details
SNRPD1, CT (Small Nuclear Ribonucleoprotein Sm D1, Sm-D1, snRNP Core Protein D1, Sm-D Autoantigen) (MaxLight 650)
MBS6500026-01 0.1 mL

SNRPD1, CT (Small Nuclear Ribonucleoprotein Sm D1, Sm-D1, snRNP Core Protein D1, Sm-D Autoantigen) (MaxLight 650)

Ask
View Details
SNRPD1, CT (Small Nuclear Ribonucleoprotein Sm D1, Sm-D1, snRNP Core Protein D1, Sm-D Autoantigen) (MaxLight 650)
MBS6500026-02 5x 0.1 mL

SNRPD1, CT (Small Nuclear Ribonucleoprotein Sm D1, Sm-D1, snRNP Core Protein D1, Sm-D Autoantigen) (MaxLight 650)

Ask
View Details
Potassium Voltage-Gated Channel Subfamily J Member 16 (KCNJ16) Antibody
abx329220-01 50 µg

Potassium Voltage-Gated Channel Subfamily J Member 16 (KCNJ16) Antibody

Ask
View Details