Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-SEPTIN12 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Septin 12 is a protein that in humans is encoded by the SEPT12 gene. This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

Mitochondrial import inner membrane translocase subunit Tim17-A; Inner membrane preprotein translocase Tim17a; TIMM17A; MIMT17; TIM17; TIM17A; TIMM17

Gene Name

SEPTIN12

Gene ID

124404

UniProt

Q8IYM1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SEPTIN12 recombinant protein (Position: K71-F358) .

Clonality

Polyclonal

Applications

Flow Cytometry

Field of Research

Cancer, Metabolism, Mitochondrial Metabolism, Organelle Proteins, Pathways and Processes, Protein Trafficking, Signal Transduction, Tumor Biomarkers

Purification

Immunogen affinity purified.

Form

Liquid

Function

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

References & Citations

1. Hall, P. A., Jung, K., Hillan, K. J., Russell, S. E. H. Expression profiling the human septin gene family. J. Path. 206: 269-278, 2005. 2. Kuo, Y.-C., Lin, Y.-H., Chen, H.-I., Wang, Y.-Y., Chiou, Y.-W., Lin, H.-H., Pan, H.-A., Wu, C.-M., Su, S.-M., Hsu, C.-C., Kuo, P.-L. SEPT12 mutations cause male infertility with defective sperm annulus. Hum. Mutat. 33: 710-719, 2012. 3. Lin, Y.-H., Chou, C.-K., Hung, Y.-C., Yu, I.-S., Pan, H.-A., Lin, S.-W., Kuo, P.-L. SEPT12 deficiency causes sperm nucleus damage and developmental arrest of preimplantation embryos. Fertil. Steril. 95: 363-365, 2011.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Translocase of inner mitochondrial membrane 17A

Subcellular Location

Mitochondrion inner membrane, Multi-pass membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CD31 / PECAM-1 (158-2B3), CF405S conjugate, 0.1mg/mL
BNC040352-100 1x 100 µL

CD31 / PECAM-1 (158-2B3), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Mucin 5AC (MUC5AC) (45M1), CF594 conjugate, 0.1mg/mL
BNC940031-100 1x 100 µL

Mucin 5AC (MUC5AC) (45M1), CF594 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Insulin (E2-E3), CF740 conjugate, 0.1mg/mL
BNC740281-500 1x 500 µL

Insulin (E2-E3), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Ep-CAM / CD326 (VU-1D9), CF514 conjugate, 0.1mg/mL
BNC140017-500 1x 500 µL

Ep-CAM / CD326 (VU-1D9), CF514 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD46 (197-2B1), CF740 conjugate, 0.1mg/mL
BNC740931-500 1x 500 µL

CD46 (197-2B1), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
P53 (BP53-12 + DO-7), CF740 conjugate, 0.1mg/mL
BNC740723-100 1x 100 µL

P53 (BP53-12 + DO-7), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details