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Anti-SEMA4F Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Semaphorin-4F is a protein that in humans is encoded by the SEMA4F gene. This gene encodes a transmembrane class IV semaphorin family protein, which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer, the development of neurofibromas, and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants.

Synonyms

Solute carrier family 2, facilitated glucose transporter member 6; Glucose transporter type 6; GLUT-6; Glucose transporter type 9; GLUT-9; SLC2A6; GLUT9

Gene Name

SEMA4F

Gene ID

10505

UniProt

O95754

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SEMA4F recombinant protein (Position: R35-E574) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in brain, spleen and peripheral blood leukocytes.

Applications

Flow Cytometry

Field of Research

Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Facilitative glucose transporter; binds cytochalasin B with low affinity.

References & Citations

1. Encinas, J. A., Kikuchi, K., Chedotal, A., de Castro, F., Goodman, C. S., Kimura, T. Cloning, expression, and genetic mapping of Sema W, a member of the semaphorin family. Proc. Nat. Acad. Sci. 96: 2491-2496, 1999.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Solute carrier family 2 member 6

Subcellular Location

Cell membrane. Multi-pass membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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