Anti-TTLL12 Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

Enables H4K20me3 modified histone binding activity and tubulin binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and regulation of mitotic cell cycle. Located in cytoplasm.

Synonyms

DAP3-binding cell death enhancer 1; Death ligand signal enhancer; DELE1; DELE; KIAA0141

Gene Name

TTLL12

Gene ID

23170

UniProt

Q14166

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TTLL12 recombinant protein (Position: E8-Q634) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

Flow Cytometry

Field of Research

Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation.

References & Citations

1. Brants, J., Semenchenko, K., Wasylyk, C., Robert, A., Carles, A., Zambrano, A., Pradeau-Aubreton, K., Birck, C., Schalken, J. A., Poch, O., de Mey, J., Wasylyk, B. Tubulin tyrosine ligase like 12, a TTLL family member with SET- and TTL-like domains and roles in histone and tubulin modifications and mitosis. PLoS One 7: e51258, 2012. 2. Gross, M. B. Personal Communication. Baltimore, Md. 6/28/2021. 3. Ju, L.-G., Zhu, Y., Lei, P.-J., Yan, D., Zhu, K., Wang, X., Li, Q.-L., Li, X.-J., Chen, J.-W., Li, L.-Y., Wu, M. TTLL12 inhibits the activation of cellular antiviral signaling through interaction with VISA/MAVS. J. Immun. 198: 1274-1284, 2017.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64099 MW

Applications Notes

Gene Name Synonym

DAP3 binding cell death enhancer 1

Subcellular Location

Mitochondrion.

Protein Name

DAP3 binding cell death enhancer 1

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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Anti-TTLL12 Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Applications Notes

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

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