Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-EF-Ts/TSFM Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

Elongation factor Ts, mitochondrial is a protein that in humans is encoded by the TSFM gene. It is an EF-Ts homolog. This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants.

Synonyms

Annexin A8 ; Annexin VIII ; Annexin-8 ; Vascular anticoagulant-beta ; VAC-beta ; ANXA8 ; ANX8

Gene Name

TSFM

Gene ID

10102

UniProt

P43897

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human EF-Ts/TSFM recombinant protein (Position: M1-E325) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

Flow Cytometry

Field of Research

Signal Transduction, Cardiovascular, Cytoskeleton, Cytoskeleton/ECM, Actin Binding Proteins, Actin, etc., Microfilaments, Cell Adhesion

Purification

Immunogen affinity purified.

Form

Liquid

Function

This protein is an anticoagulant protein that acts as an in inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

References & Citations

1. Ahola, S., Isohanni, P., Euro, L., Brilhante, V., Palotie, A., Pihko, H., Lonnqvist, T., Lehtonen, T., Laine, J., Tyynismaa, H., Suomalainen, A. Mitochondrial EFTs defects in juvenile-onset Leigh disease, ataxia, neuropathy, and optic atrophy. Neurology 83: 743-751, 2014. 2. Shamseldin, H. E., Alshammari, M., Al-Sheddi, T., Salih, M. A., Alkhalidi, H., Kentab, A., Repetto, G. M., Hashem, M., Alkuraya, F. S. Genomic analysis of mitochondrial diseases in a consanguineous population reveals novel candidate disease genes. J. Med. Genet. 49: 234-241, 2012. 3. Smeitink, J. A. M., Elpeleg, O., Antonicka, H., Diepstra, H., Saada, A., Smits, P., Sasarman, F., Vriend, G., Jacob-Hirsch, J., Shaag, A., Rechavi, G., Welling, B., Horst, J., Rodenburg, R. J., van den Heuvel, B., Shoubridge, E. A. Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs. Am. J. Hum. Genet. 79: 869-877, 2006.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

36881 MW

Applications Notes

6

Gene Name Synonym

Annexin A8

Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Protein Name

Annexin A8

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

Suc-Ala-Ala-Pro-Trp-pNA
MF-0126983-01 10 mg

Suc-Ala-Ala-Pro-Trp-pNA

Sign In for Pricing
View Details
Suc-Ala-Ala-Pro-Trp-pNA
MF-0126983-02 50 mg

Suc-Ala-Ala-Pro-Trp-pNA

Sign In for Pricing
View Details
Lentiviral human GAL shRNA (UAS) - Lentiviral human GAL shRNA (UAS) (25)
GTR15087869 1 Vial

Lentiviral human GAL shRNA (UAS) - Lentiviral human GAL shRNA (UAS) (25)

Sign In for Pricing
View Details
Omalizumab Polyclonal Antibody
E55A01754 100 µg

Omalizumab Polyclonal Antibody

Sign In for Pricing
View Details
1-Butylpyrrolidin-2-one
TRC-B700583-500MG 500 mg

1-Butylpyrrolidin-2-one

Sign In for Pricing
View Details
Sheep Anti-centriole and centrosome antibody IgA ELISA Kit
MBS744756-01 48 Well

Sheep Anti-centriole and centrosome antibody IgA ELISA Kit

Sign In for Pricing
View Details