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Anti-LIN41/TRIM71 Antibody Picoband®

Boster Bio Anti-LIN41/TRIM71 Antibody Picoband® catalog # A08005-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

The protein encoded by this gene is an E3 ubiquitin-protein ligase that binds with miRNAs and maintains the growth and upkeep of embryonic stem cells. This gene also is involved in the G1-S phase transition of the cell cycle.

Synonyms

BMP and activin membrane-bound inhibitor homolog; Non-metastatic gene A protein; Putative transmembrane protein; NMA; BAMBI; NMA

Gene Name

TRIM71

Gene ID

131405

UniProt

Q2Q1W2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human LIN41/TRIM71 recombinant protein (Position: E85-F868) .

Clonality

Polyclonal

Tissue Specificity

Expressed in adult liver.

Applications

WB, IHC, Flow Cytometry, ELISA

Field of Research

Atherosclerosis, Cardiovascular, Chaperones, Heat Shock Proteins, Protein Trafficking, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Negatively regulates TGF-beta signaling.

References & Citations

1. Furey, C. G., Choi, J., Jin, S. C., Zeng, X., Timberlake, A. T., Nelson-Williams, C., Mansuri, M. S., Lu, Q., Duran, D., Panchagnula, S., Allocco, A., Karimy, J. K., and 33 others. De novo mutation in genes regulating neural stem cell fate in human congenital hydrocephalus. Neuron 99: 302-314, 2018. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/4/2019. 3. Lancman, J. J., Caruccio, N. C., Harfe, B. D., Pasquinelli, A. E., Schageman, J. J., Pertsemlidis, A., Fallon, J. F. Analysis of the regulation of lin-41 during chick and mouse limb development. Dev. Dyn. 234: 948-960, 2005.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

17136 MW

Observed Molecular Weight

93 kDa

Applications Notes

6

Gene Name Synonym

BMP and activin membrane bound inhibitor

Subcellular Location

Cytoplasm . Nucleus . Translocates to nuclear foci during heat shock.

Protein Name

Chromaffin granule amine transporter

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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