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Anti-TRIL Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

KIAA0644, also known as TRIL or TLR4 interactor with leucine rich repeats, is a protein that in humans is encoded by the KIAA0644 gene. TRIL is a component of the TLR4 (603030) complex and is induced in a number of cell types by lipopolysaccharide (LPS) .

Synonyms

B-cell differentiation antigen CD72; Lyb-2; CD72; CD72

Gene Name

TRIL

Gene ID

9865

UniProt

Q7L0X0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TRIL recombinant protein (Position: V26-Q696) .

Clonality

Polyclonal

Tissue Specificity

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells

Purification

Immunogen affinity purified.

Form

Liquid

Function

Plays a role in B-cell proliferation and differentiation.

References & Citations

1. Carpenter, S., Carlson, T., Dellacasagrande, J., Garcia, A., Gibbons, S., Hertzog, P., Lyons, A., Lin, L.-L., Lynch, M., Monie, T., Murphy, C., Seidl, K. J., Wells, C., Dunne, A., O'Neill, L. A. J. TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain. J. Immun. 183: 3989-3995, 2009. 2. Gross, M. B. Personal Communication. Baltimore, Md. 4/26/2010. 3. Ishikawa, K., Nagase, T., Suyama, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 169-176, 1998.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

CD72 molecule

Subcellular Location

Membrane; Single-pass type II membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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