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Anti-SLC7A3 Antibody Picoband® Fluoro594 Conjugated

Selected Variant

A09720-3-Fluoro594

Size: 100 µg/Vial

Product Specifications

Background

Cationic amino acid transporter 3 is a protein that in humans is encoded by the SLC7A3 gene. This gene encodes a member of the solute carrier family 7. The encoded protein is a sodium-independent cationic amino acid transporter. Alternate splicing results in multiple transcripts that encoded the same protein. The International Radiation Hybrid Mapping Consortium mapped the SLC7A3 gene to the X chromosome.

Synonyms

Cationic amino acid transporter 3; CAT-3; CAT3; Cationic amino acid transporter y+; Solute carrier family 7 member 3; SLC7A3; ATRC3, CAT3

Gene Name

SLC7A3

Gene ID

84889

UniProt

Q8WY07

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human SLC7A3.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala. .

Applications

Flow Cytometry

Field of Research

Amino Acid Metabolism, Amino Acids, Cancer, Channels, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner. .

References & Citations

1. Ito K, Groudine M (1997) . A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain.. J. Biol. Chem. 272 (42) : 26780–6. 2. Gilles W, Vulcu SD, Liewald JF, et al. (2005) . Monovalent cation conductance in Xenopus laevis oocytes expressing hCAT-3.. Biochim. Biophys. Acta.1668 (2) : 234–9. 3. Vekony, N., Wolf, S., Boissel, J.-P., Gnauert, K., Closs, E. I. Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues. Biochemistry 40: 12387-12394, 2001.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

67169 MW

Applications Notes

6

Gene Name Synonym

Cationic amino acid transporter 3

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

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