Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-SDE2 Antibody Picoband®

Boster Bio Anti-SDE2 Antibody Picoband® catalog # A15473-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Enables damaged DNA binding activity. Involved in several processes, including cellular response to UV; mitotic G1 DNA damage checkpoint signaling; and protein ubiquitination. Located in several cellular components, including Golgi apparatus; cytosol; and nuclear speck.

Synonyms

Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1; KBTBD2; BKLHD1; KIAA1489

Gene Name

SDE2

Gene ID

163859

UniProt

Q6IQ49

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SDE2 recombinant protein (Position: I10-K447) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

ELISA, Flow Cytometry, IF, IHC, ICC, WB

Field of Research

Cell Biology

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

References & Citations

1. Jess, F. , Anqi, D. , Abigail, M. , Alexandra, M. M. , Neilj, G. , & Daniel, C. , et al. Sde2 is an essential gene required for ribosome biogenesis and the regulation of alternative splicing. Nucleic Acids Research (16), 16. 2. Rageul, J. , Park, J. J. , Zeng, P. P. , Lee, E. A. , & Kim, H. . Sde2 integrates into the timeless-tipin complex to protect stalled replication forks. Nature Communications. 3. Julie, R. , Park, J. J. , Ukhyun, J. , Weinheimer, A. S. , Vu, T. T. M. , & Hyungjin, K. . (2019) . Conditional degradation of sde2 by the arg/n-end rule pathway regulates stress response at replication forks. Nuclc Acids Research (8), 8.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

24145 MW

Observed Molecular Weight

54 kDa

Applications Notes

6

Gene Name Synonym

Kelch repeat and BTB domain containing 2

Subcellular Location

Cul3-RING ubiquitin ligase complex.

Protein Name

Transmembrane protein 240

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RAI14 Rabbit Polyclonal Antibody
TA333808 100 µL

RAI14 Rabbit Polyclonal Antibody

Ask
View Details
RHPN1, CT (RHPN1, KIAA1929, Rhophilin-1, GTP-Rho-binding protein 1) (AP)
MBS6342049-01 0.2 mL

RHPN1, CT (RHPN1, KIAA1929, Rhophilin-1, GTP-Rho-binding protein 1) (AP)

Ask
View Details
RHPN1, CT (RHPN1, KIAA1929, Rhophilin-1, GTP-Rho-binding protein 1) (AP)
MBS6342049-02 5x 0.2 mL

RHPN1, CT (RHPN1, KIAA1929, Rhophilin-1, GTP-Rho-binding protein 1) (AP)

Ask
View Details
Myb-binding protein 1A (MYBBP1A, p160) (HRP)
M9600-04-HRP 100 µL

Myb-binding protein 1A (MYBBP1A, p160) (HRP)

Ask
View Details
DYNC1LI1 Overexpression Lysate (Native) - (Dry Ice)
NBP2-07086 0.1 mg

DYNC1LI1 Overexpression Lysate (Native) - (Dry Ice)

Ask
View Details
Hexamidine-d12 dihydrochloride
sc-491636 1 mg

Hexamidine-d12 dihydrochloride

Ask
View Details