ASB14780
ASB14780 is a 4-phenoxy derivative, the cytosolic Phospholipase A2α (cPLA2α) inhibitor, with an IC50 value of 20 nM[1].
Product Specifications
CAS Number
[1069046-00-9]
Product Name Alternative
MK-0869; MK-869; L-754030
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/asb14780.html
Concentration
10mM
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCC1=CC(C(CCC2=CC=CC=C2)=CN3C4=CC=C(C=C4)OC5=CC=CC=C5)=C3C=C1)O.OCC(CO)(CO)N
Molecular Formula
C35H38N2O6
Molecular Weight
582.69
References & Citations
[1]Tomoo T, et al. Design, synthesis, and biological evaluation of 3- (1-Aryl-1H-indol-5-yl) propanoic acids as new indole-based cytosolic phospholipase A2α inhibitors. J Med Chem. 2014. 57 (17) :7244-62.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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