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Anti-SAMSN1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

SAMSN1 is a member of a novel protein family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains.SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains.

Synonyms

Immunoglobulin lambda-like polypeptide 1; CD179 antigen-like family member B; Ig lambda-5; Immunoglobulin omega polypeptide; Immunoglobulin-related protein 14.1; CD179b; IGLL1; IGL1

Gene Name

SAMSN1

Gene ID

64092

UniProt

Q9NSI8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SAMSN1 recombinant protein (Position: E99-D373) .

Clonality

Polyclonal

Tissue Specificity

Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative) .

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Immunoglobulins, Immunology

Purification

Immunogen affinity purified.

Form

Liquid

Function

Critical for B-cell development.

References & Citations

1. Claudio, J. O., Zhu, Y. X., Benn, S. J., Shukla, A. H., McGlade, C. J., Falcioni, N., Stewart, A. K. HACS1 encodes a novel SH3-SAM adaptor protein differentially expressed in normal and malignant hematopoietic cells. Oncogene 20: 5373-5377, 2001. 2. Mitelman, F., Mertens, F., Johansson, B. A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nature Genet. 15: 417-474, 1997. 3. Zhu, Y. X., Benn, S., Li, Z. H., Wei, E., Masih-Khan, E., Trieu, Y., Bali, M., McGlade, C. J., Claudio, J. O., Stewart, A. K. The SH3-SAM adaptor HACS1 is up-regulated in B cell activation signaling cascades. J. Exp. Med. 200: 737-747, 2004.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Immunoglobulin lambda like polypeptide 1

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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