Anti-WDR44 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
WD repeat-containing protein 44 is a protein that in humans is encoded by the WDR44 gene. This gene encodes a protein that interacts with the small GTPase rab11. A similar protein in rat binds the GTP-containing active form of rab11. This protein may play a role in endosome recycling. Alternate splicing results in multiple transcript variants.
Synonyms
Solute carrier family 2, facilitated glucose transporter member 6; Glucose transporter type 6; GLUT-6; Glucose transporter type 9; GLUT-9; SLC2A6; GLUT9
Gene Name
WDR44
Gene ID
54521
UniProt
Q5JSH3
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human WDR44 recombinant protein (Position: D188-S913) .
Clonality
Polyclonal
Tissue Specificity
Highly expressed in brain, spleen and peripheral blood leukocytes.
Applications
Flow Cytometry
Field of Research
Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction
Purification
Immunogen affinity purified.
Form
Liquid
Function
Facilitative glucose transporter; binds cytochalasin B with low affinity.
References & Citations
1. Gross, M. B. Personal Communication. Baltimore, Md. 2/15/2022. 2. Mammoto, A., Ohtsuka, T., Hotta, I., Sasaki, T., Takai, Y. Rab11BP/rabphilin-11, a downstream target of Rab11 small G protein implicated in vesicle recycling. J. Biol. Chem. 274: 25517-25524, 1999. 3. Walia, V., Cuenca, A., Vetter, M., Insinna, C., Perera, S., Lu, Q., Ritt, D. A., Semier, E., Specht, S., Stauffer, J., Morrison, D. K., Lorentzen, E., Westlake, C. J. Akt regulates a Rab11-effector switch required for ciliogenesis. Dev. Cell 50: 229-246, 2019.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Solute carrier family 2 member 6
Subcellular Location
Cell membrane. Multi-pass membrane protein.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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