Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TSPYL5 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

TSPY like 5 is a protein that in humans is encoded by the TSPYL5 gene. Predicted to enable chromatin binding activity and histone binding activity. Involved in several processes, including cellular response to gamma radiation; positive regulation of protein kinase B signaling; and positive regulation of protein ubiquitination. Predicted to be active in chromatin and nucleus.

Synonyms

RNA-binding protein Nova-2; Astrocytic NOVA1-like RNA-binding protein; Neuro-oncological ventral antigen 2; NOVA2; ANOVA; NOVA3

Gene Name

TSPYL5

Gene ID

85453

UniProt

Q86VY4

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TSPYL5 recombinant protein (Position: R24-Q337) .

Clonality

Polyclonal

Tissue Specificity

Brain. Expression restricted to astrocytes.

Applications

Flow Cytometry

Field of Research

Channels, Metabolism, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

May regulate RNA splicing or metabolism in a specific subset of developing neurons. Binds single strand RNA.

References & Citations

1. Epping, M. T., Meijer, L. A. T., Krijgsman, O., Bos, J. L., Pandolfi, P. P., Bernards, R. TSPYL5 suppresses p53 levels and function by physical interaction with USP7. Nature Cell Biol. 13: 102-108, 2011. 2. Jung, Y., Park, J., Bang, Y.-J., Kim, T.-Y. Gene silencing of TSPYL5 mediated by aberrant promoter methylation in gastric cancers. Lab. Invest. 88: 153-160, 2008. 3. Kim, E. J., Lee, S. Y., Kim, T. R., Choi, S. I., Cho, E. W., Kim, K. C., Kim, I. G. TSPYL5 is involved in cell growth and the resistance to radiation in A549 cells via the regulation of p21 (WAF1/Cip1) and PTEN/AKT pathway. Biochem. Biophys. Res. Commun. 392: 448-453, 2010.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

29370 MW

Applications Notes

6

Gene Name Synonym

NOVA alternative splicing regulator 2

Subcellular Location

Nucleus.

Protein Name

Aquaporin-6

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

C3orf54 Rabbit pAb
E47R9832 100 µL

C3orf54 Rabbit pAb

Sign In for Pricing
View Details
Human SPANXN3 ELISA KIT
ELI-53434h 96 Tests

Human SPANXN3 ELISA KIT

Sign In for Pricing
View Details
Syt1 Rat shRNA Plasmid (Locus ID 25716)
TR703195 1 Kit

Syt1 Rat shRNA Plasmid (Locus ID 25716)

Sign In for Pricing
View Details
ST3GAL3 (SIAT6, CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase, Beta-galactoside alpha-2,3-sialyltransferase 3, Gal beta-1,3 (4) GlcNAc alpha-2,3 sialyltransferase, N-acetyllactosaminide alpha-2,3-sialyltransferase, ST3Gal III, ST3N, Sialyltransferase 6) (Not for Export EU)
133896 100 µL

ST3GAL3 (SIAT6, CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase, Beta-galactoside alpha-2,3-sialyltransferase 3, Gal beta-1,3 (4) GlcNAc alpha-2,3 sialyltransferase, N-acetyllactosaminide alpha-2,3-sialyltransferase, ST3Gal III, ST3N, Sialyltransferase 6) (Not for Export EU)

Sign In for Pricing
View Details
NF-kappaB p105/p50 Antibody
MBS9504220-01 0.05 mL

NF-kappaB p105/p50 Antibody

Sign In for Pricing
View Details
NF-kappaB p105/p50 Antibody
MBS9504220-02 0.1 mL

NF-kappaB p105/p50 Antibody

Sign In for Pricing
View Details