Anti-TRIR Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Enables 3'-5' exonuclease activity and 5'-3' exonuclease activity. Involved in RNA phosphodiester bond hydrolysis, exonucleolytic and rRNA catabolic process.
Synonyms
Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29
Gene Name
TRIR
Gene ID
79002
UniProt
Q9BQ61
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human TRIR, identical to the related mouse sequences.
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed.
Applications
Flow Cytometry
Field of Research
Chemokines, Immunology, Innate Immunity
Purification
Immunogen affinity purified.
Form
Liquid
Function
Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.
References & Citations
1. Xie, J. , Zhen, C. , Zhang, X. , Chen, H. , & Guan, W. . (2017) . Identification of an rnase that preferentially cleaves a/g nucleotides. Scientific Reports, 7, 45207. 2. Huang, X. , Leduc, R. D. , Fornelli, L. , Schunter, A. J. , Bennett, R. L. , & Kelleher, N. L. , et al. (2019) . Defining the nsd2 interactome: parp1 parylation reduces nsd2 histone methyltransferase activity and impedes chromatin binding. Journal of Biological Chemistry. 3. Kim, H. , Dejsuphong, D. , Adelmant, G. , Ceccaldi, R. , & D'Andrea, A. D. . (2014) . Transcriptional repressor zbtb1 promotes chromatin remodeling and translesion dna synthesis. Molecular Cell, 54 (1) .
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
14377 MW
Applications Notes
6
Gene Name Synonym
Retrotransposon Gag like 10
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Protein Name
Lymphocyte antigen 6A-2/6E-1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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