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Anti-TRIR Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Enables 3'-5' exonuclease activity and 5'-3' exonuclease activity. Involved in RNA phosphodiester bond hydrolysis, exonucleolytic and rRNA catabolic process.

Synonyms

Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29

Gene Name

TRIR

Gene ID

79002

UniProt

Q9BQ61

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human TRIR, identical to the related mouse sequences.

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

Flow Cytometry

Field of Research

Chemokines, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Form

Liquid

Function

Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.

References & Citations

1. Xie, J. , Zhen, C. , Zhang, X. , Chen, H. , & Guan, W. . (2017) . Identification of an rnase that preferentially cleaves a/g nucleotides. Scientific Reports, 7, 45207. 2. Huang, X. , Leduc, R. D. , Fornelli, L. , Schunter, A. J. , Bennett, R. L. , & Kelleher, N. L. , et al. (2019) . Defining the nsd2 interactome: parp1 parylation reduces nsd2 histone methyltransferase activity and impedes chromatin binding. Journal of Biological Chemistry. 3. Kim, H. , Dejsuphong, D. , Adelmant, G. , Ceccaldi, R. , & D'Andrea, A. D. . (2014) . Transcriptional repressor zbtb1 promotes chromatin remodeling and translesion dna synthesis. Molecular Cell, 54 (1) .

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

14377 MW

Applications Notes

6

Gene Name Synonym

Retrotransposon Gag like 10

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Name

Lymphocyte antigen 6A-2/6E-1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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