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Anti-TRIM50 Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

Tripartite motif-containing 50, also known as TRIM50, is a human gene. Enables identical protein binding activity. Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within regulation of establishment of protein localization. Located in cytosol.

Synonyms

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

Gene Name

TRIM50

Gene ID

135892

UniProt

Q86XT4

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human TRIM50 recombinant protein (Position: K243-L487) .

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Applications

Flow Cytometry

Field of Research

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Form

Liquid

Function

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

References & Citations

1. Micale, L., Fusco, C., Augello, B., Napolitano, L. M. R., Dermitzakis, E. T., Meroni, G., Merla, G., Reymond, A. Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase. Europ. J. Hum. Genet. 16: 1038-1049, 2008.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64099 MW

Applications Notes

6

Gene Name Synonym

RNA-binding protein 47

Subcellular Location

Nucleus .

Protein Name

Follicular dendritic cell secreted peptide

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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