Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TMC7 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Predicted to enable mechanosensitive ion channel activity. Predicted to be involved in ion transmembrane transport. Predicted to be integral component of plasma membrane.

Synonyms

Interactor of HORMAD1 protein 1; Cancer/testis antigen 74; CT74; Coiled-coil domain-containing protein 36; CCDC36; IHO1

Gene Name

TMC7

Gene ID

79905

UniProt

Q7Z402

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TMC7 recombinant protein (Position: A8-N723) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

Flow Cytometry

Field of Research

Cell Biology

Purification

Immunogen affinity purified.

Form

Liquid

Function

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

References & Citations

1. Keresztes, G., Mutai, H., Heller, S. The TMC and EVER genes belong to a larger protein family, the TMC gene family encoding transmembrane proteins. BMC Genomics 4: 24, 2003. Note: Electronic Article. 2. Kurima, K., Yang, Y., Sorber, K., Griffith, A. J. Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis. Genomics 82: 300-308, 2003.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64099 MW

Applications Notes

6

Gene Name Synonym

Coiled-coil domain containing 36

Subcellular Location

Chromosome.

Protein Name

DAP3 binding cell death enhancer 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Human SALa (Salusin Alpha) ELISA Kit
ELK10388-01 48 Tests

Human SALa (Salusin Alpha) ELISA Kit

Ask
View Details
Human SALa (Salusin Alpha) ELISA Kit
ELK10388-02 96 Tests

Human SALa (Salusin Alpha) ELISA Kit

Ask
View Details
Human SALa (Salusin Alpha) ELISA Kit
ELK10388-03 5x 96 Tests

Human SALa (Salusin Alpha) ELISA Kit

Ask
View Details
Rabbit anti-Shigella flexneri CLCA Polyclonal Antibody
MBS7160913 Inquire

Rabbit anti-Shigella flexneri CLCA Polyclonal Antibody

Ask
View Details
Recombinant Human Acrosomal Protein SP-10/ACRV1 (C-6His)
32-7377-50 50 µg

Recombinant Human Acrosomal Protein SP-10/ACRV1 (C-6His)

Ask
View Details
EAN57, NT (TEX33, C22orf33, EAN57, Testis-expressed sequence 33 protein) (MaxLight 490)
MBS6294132-01 0.1 mL

EAN57, NT (TEX33, C22orf33, EAN57, Testis-expressed sequence 33 protein) (MaxLight 490)

Ask
View Details