Anti-FRY Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Predicted to enable enzyme inhibitor activity. Predicted to be involved in cell morphogenesis and neuron projection development. Predicted to be located in microtubule organizing center and spindle pole. Predicted to be active in cell cortex and site of polarized growth.
Synonyms
Mannose-binding protein C; MBP-C; Mannan-binding protein; RA-reactive factor P28A subunit; RARF/P28A; Mbl2
Gene Name
FRY
Gene ID
10129
UniProt
Q5TBA9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human FRY recombinant protein (Position: E11-L3013) .
Clonality
Polyclonal
Tissue Specificity
Found only in peripheral nervous system Schwann cells.
Applications
Flow Cytometry
Field of Research
Complement, Immunology, Innate Immunity
Purification
Immunogen affinity purified.
Form
Liquid
Function
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity) .
References & Citations
1. Gallegos, M. E., Bargmann, C. I. Mechanosensory neurite termination and tiling depend on SAX-2 and the SAX-1 kinase. Neuron 44: 239-249, 2004. 2. Hartz, P. A. : Personal Communication. Baltimore, Md. , 9/11/2012. 3. Ikeda, M., Chiba, S., Ohashi, K., Mizuno, K. Furry protein promotes Aurora A-mediated polo-like kinase 1 activation. J. Biol. Chem. 287: 27670-27681, 2012.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Mannose-binding lectin (protein C) 2
Subcellular Location
Secreted.
Protein Name
D (4) dopamine receptor
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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