Anti-MSY2/YBOX2/YBX2 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Y-box-binding protein 2 is a protein that in humans is encoded by the YBX2 gene. This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15.
Synonyms
Gap junction gamma-1 protein; Connexin-45; Cx45; Gap junction alpha-7 protein; GJC1; GJA7
Gene Name
YBX2
Gene ID
51087
UniProt
Q9Y2T7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human MSY2/YBOX2/YBX2 recombinant protein (Position: E211-E364) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed.
Applications
Flow Cytometry
Field of Research
Cell Adhesion, Cytoskeleton/ECM, Signal Transduction
Purification
Immunogen affinity purified.
Form
Liquid
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
References & Citations
1. Gu, W., Tekur, S., Reinbold, R., Eppig, J. J., Choi, Y.-C., Zheng, J. Z., Murray, M. T., Hecht, N. B. Mammalian male and female germ cells express a germ cell-specific Y-box protein, MSY2. Biol. Reprod. 59: 1266-1274, 1998. 2. Kohno, Y., Matsuki, Y., Tanimoto, A., Izumi, H., Uchiumi, T., Kohno, K., Shimajiri, S., Sasaguri, Y. Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen. Brit. J. Cancer 94: 710-716, 2006. 3. Tekur, S., Pawlak, A., Guellaen, G., Hecht, N. B. Contrin, the human homologue of a germ-cell Y-box-binding protein: cloning, expression, and chromosomal localization. J. Androl. 20: 135-144, 1999.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
45470 MW
Applications Notes
6
Gene Name Synonym
Gap junction gamma-1 protein
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein Name
Gap junction gamma-1 protein
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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