What sizes are available for Anti-THAP11 Antibody Picoband® Fluoro647 Conjugated?

Anti-THAP11 Antibody Picoband® Fluoro647 Conjugated is available in the following size(s): 100 µg/Vial.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

Anti-THAP11 Antibody Picoband® Fluoro647 Conjugated

Q: What is the catalog number for Anti-THAP11 Antibody Picoband® Fluoro647 Conjugated?

The catalog number for Anti-THAP11 Antibody Picoband® Fluoro647 Conjugated is A08519-2-Fluoro647.

Q: Is Anti-THAP11 Antibody Picoband® Fluoro647 Conjugated in stock?

Anti-THAP11 Antibody Picoband® Fluoro647 Conjugated is currently made to order / not held in immediate stock. Contact us for lead time.

Product Specifications

Background

The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases.

Synonyms

PHD finger protein 21A; BHC80a; BRAF35-HDAC complex protein BHC80; PHF21A; BHC80; KIAA1696; BM-006

Gene Name

THAP11

Gene ID

57215

UniProt

Q96EK4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human THAP11 recombinant protein (Position: M1-E294) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in brain. Expressed at much lower level in other tissues.

Applications

Flow Cytometry

Field of Research

Cancer, Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Metalloprotease, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation.

References & Citations

1. Dejosez, M., Krumenacker, J. S., Zitur, L. J., Passeri, M., Chu, L.-F., Songyang, Z., Thomson, J. A., Zwaka, T. P. Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells. Cell 133: 1162-1174, 2008. Note: Erratum: Cell 134: 692 only, 2008. 2. Roussigne, M., Kossida, S., Lavigne, A.-C., Clouaire, T., Ecochard, V., Glories, A., Amalric, F., Girard, J.-P. The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. Trends Biochem. Sci. 28: 66-69, 2003.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

Gene Name Synonym

PHD finger protein 21A

Subcellular Location

Nucleus.

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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