Anti-RDH10 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development.
Synonyms
Prorelaxin H1; Relaxin B chain; Relaxin A chain; RLN1
Gene Name
RDH10
Gene ID
157506
UniProt
Q8IZV5
Host
Rabbit
Reactivity
Human, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human RDH10 recombinant protein (Position: M1-I341) .
Clonality
Polyclonal
Tissue Specificity
Prostate. Not expressed in placenta, decidua or ovary.
Applications
Flow Cytometry
Field of Research
Cell Type Markers, Growth Factors/Hormones, Signal Transduction, Tags & Cell Markers
Purification
Immunogen affinity purified.
Form
Liquid
Function
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
References & Citations
1. Sandell, L. L., Sanderson, B. W., Moiseyev, G., Johnson, T., Mushegian, A., Young, K., Rey, J.-P., Ma, J., Staehling-Hampton, K., Trainor, P. A. RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. Genes Dev. 21: 1113-1124, 2007. 2. Wu, B. X., Chen, Y., Chen, Y., Fan, J., Rohrer, B., Crouch, R. K., Ma, J. Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE. Invest. Ophthal. Vis. Sci. 43: 3365-3372, 2002.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Subcellular Location
Secreted.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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