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Anti-RDH10 Antibody Picoband®

Boster Bio Anti-RDH10 Antibody Picoband® catalog # A08376-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development.

Synonyms

Prorelaxin H1; Relaxin B chain; Relaxin A chain; RLN1

Gene Name

RDH10

Gene ID

157506

UniProt

Q8IZV5

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RDH10 recombinant protein (Position: M1-I341) .

Clonality

Polyclonal

Tissue Specificity

Prostate. Not expressed in placenta, decidua or ovary.

Applications

WB, Flow Cytometry, ELISA

Field of Research

Cell Type Markers, Growth Factors/Hormones, Signal Transduction, Tags & Cell Markers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.

References & Citations

1. Sandell, L. L., Sanderson, B. W., Moiseyev, G., Johnson, T., Mushegian, A., Young, K., Rey, J.-P., Ma, J., Staehling-Hampton, K., Trainor, P. A. RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. Genes Dev. 21: 1113-1124, 2007. 2. Wu, B. X., Chen, Y., Chen, Y., Fan, J., Rohrer, B., Crouch, R. K., Ma, J. Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE. Invest. Ophthal. Vis. Sci. 43: 3365-3372, 2002.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

38 kDa

Applications Notes

6

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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