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Anti-ERp72/PDIA4 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. This protein, when bound to cyclophilin B, enhances the rate of immunoglobulin G intermolecular disulfide bonding and antibody assembly.

Synonyms

Interleukin-18-binding protein; IL-18BP; Interferon gamma-inducing factor-binding protein; Il18bp; Igifbp

Gene Name

PDIA4

Gene ID

9601

UniProt

P13667

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human ERp72/PDIA4 recombinant protein (Position: K59-K544) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

Flow Cytometry

Field of Research

Interleukins

Purification

Immunogen affinity purified.

Form

Liquid

Function

Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response (By similarity) . .

References & Citations

1. Ewing, R. M., Chu, P., Elisma, F., Li, H., Taylor, P., Climie, S., ... & Figeys, D. (2007) . Large‐scale mapping of human protein–protein interactions by mass spectrometry. Molecular systems biology, 3 (1), 89.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

67166 MW

Applications Notes

6

Gene Name Synonym

Interleukin 18 binding protein

Subcellular Location

Secreted.

Protein Name

Suppressor of tumorigenicity 7 protein

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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