Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Heme Oxygenase 1/HMOX1 Antibody Picoband®

Boster Bio Anti-Heme Oxygenase 1/HMOX1 Antibody Picoband® catalog # A00253-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

HMOX1 (heme oxygenase (decycling) 1), also known as HO-1, is a human gene that encodes for the enzyme heme oxygenase 1. It is an essential enzyme in heme catabolism, it cleaves heme to form biliverdin. HMOX1 belongs to the heme oxygenase family. The HMOX1 gene is located on the long (q) arm of chromosome 22 at position 12.3, from base pair 34,101,636 to base pair 34,114,748. HMOX1, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. HMOX1 activity is induced by its substrate heme and by various nonheme substances.

Synonyms

Angiotensin-converting enzyme; ACE; Dipeptidyl carboxypeptidase I; Kininase II; CD143; Angiotensin-converting enzyme, soluble form; Ace; Dcp1

Gene Name

HMOX1

Gene ID

3162

UniProt

P09601

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Heme Oxygenase 1/HMOX1 recombinant protein (Position: E19-R269) .

Clonality

Polyclonal

Tissue Specificity

Testis-specific isoform is expressed in spermatocytes, adult testis.

Applications

WB, Flow Cytometry, ELISA

Field of Research

Cancer, Cancer Metabolism, Cardiovascular, Cell Biology, Cofactors, Vitamins/Minerals, Hematopoietic Progenitors, Metabolism, Metabolism Processes, Metalloprotease, Pathways and Processes, Proteolysis/Ubiquitin, Proteolytic Enzymes, Response To Hypoxia, Serum Proteins, Signal Transduction, Stem Cells, Surface Molecules, Vasculature, Vitamins/Minerals

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm.

References & Citations

1. He, C. H., Gong, P., Hu, B., Stewart, D., Choi, M. E., Choi, A. M. K., Alam, J.Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein: implication for heme oxygenase-1 gene regulation. J. Biol. Chem. 276: 20858-20865, 2001. 2. Piantadosi CA, Withers CM, Bartz RR, MacGarvey NC, Fu P, Sweeney TE, Welty-Wolf KE, Suliman HB (May 2011) . Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression. J. Biol. Chem.286 (18) : 16374–85.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00253-2

Product MSDS

https://www.bosterbio.com/msds?sku=A00253-2

Observed Molecular Weight

33 kDa

Applications Notes

6

Gene Name Synonym

Angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

Subcellular Location

Angiotensin-converting enzyme, soluble form: Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CISD1 Antibody
46503 100 µL

CISD1 Antibody

Ask
View Details
Human Chromosome 19 open reading frame 80 (C19orf80) ELISA Kit
MBS166717-01 48 Well

Human Chromosome 19 open reading frame 80 (C19orf80) ELISA Kit

Ask
View Details
Human Chromosome 19 open reading frame 80 (C19orf80) ELISA Kit
MBS166717-02 96 Well

Human Chromosome 19 open reading frame 80 (C19orf80) ELISA Kit

Ask
View Details
Human Chromosome 19 open reading frame 80 (C19orf80) ELISA Kit
MBS166717-03 5x 96 Well

Human Chromosome 19 open reading frame 80 (C19orf80) ELISA Kit

Ask
View Details
Human Chromosome 19 open reading frame 80 (C19orf80) ELISA Kit
MBS166717-04 10x 96 Well

Human Chromosome 19 open reading frame 80 (C19orf80) ELISA Kit

Ask
View Details
WARS Protein (N-His, Human)
P529544 100 µg

WARS Protein (N-His, Human)

Ask
View Details