Anti-Epoxide hydrolase/EPHX1 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Epoxide hydrolase 1 is an enzyme encoded by the EPHX1 gene in humans. Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Synonyms

Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor; FSHR; LGR1

Gene Name

EPHX1

Gene ID

2052

UniProt

P07099

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Epoxide hydrolase/EPHX1 recombinant protein (Position: A42-Q455) .

Clonality

Polyclonal

Tissue Specificity

Sertoli cells and ovarian granulosa cells.

Applications

Flow Cytometry

Field of Research

Endocrine System, G Protein Signaling, More Gpcr, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway

Purification

Immunogen affinity purified.

Form

Liquid

Function

Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

References & Citations

1. Brown, S., Chalmers, D. E. Microsomal epoxide hydrolase activity in human x mouse hybrid cells. Biochem. Biophys. Res. Commun. 137: 775-780, 1986. 2. Hamosh, A. Personal Communication. Baltimore, Md. September 20, 2017. 3. Hartsfield, J. K., Jr., Sutcliffe, M. J., Everett, E. T., Hassett, C., Omiecinski, C. J., Saari, J. A. Assignment of microsomal epoxide hydrolase (EPHX1) to human chromosome 1q42.1 by in situ hybridization. Cytogenet. Cell Genet. 83: 44-45, 1998.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

78265 MW

Applications Notes

Gene Name Synonym

Follicle-stimulating hormone receptor

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Name

Follicle-stimulating hormone receptor (FSH-R)

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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Anti-Epoxide hydrolase/EPHX1 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Applications Notes

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

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