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Anti-USP26 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains. It is specifically expressed in testis tissue. Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility.

Synonyms

Protein SOX-15; Protein SOX-12; Protein SOX-20; SOX15; SOX12; SOX20; SOX26; SOX27

Gene Name

USP26

Gene ID

83844

UniProt

Q9BXU7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human USP26 recombinant protein (Position: M1-K762) .

Clonality

Polyclonal

Tissue Specificity

Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

Applications

Flow Cytometry

Field of Research

Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

Immunogen affinity purified.

Form

Liquid

Function

Binds to the 5'-AACAAT-3' sequence.

References & Citations

1. Ma, Q., Li, Y., Guo, H., Li, C., Chen, J., Luo, M., Jiang, Z., Li, H., Gui, Y. A novel missense mutation in USP26 gene is associated with nonobstructive azoospermia. Reprod. Sci. 23: 1434-1441, 2016. 2. Ravel, C., El Houate, B., Chantot, S., Lourenco, D., Dumaine, A., Rouba, H., Bandyopadahyay, A., Radhakrishna, U., Das, B., Sengupta, S., Mandelbaum, J., Siffroi, J. P., McElreavey, K. Haplotypes, mutations and male fertility: the story of the testis-specific ubiquitin protease USP26. Molec. Hum. Reprod. 12: 643-646, 2006. 3. Stouffs, K., Lissens, W., Tournaye, H., Van Steirteghem, A., Liebaers, I. Possible role of USP26 in patients with severely impaired spermatogenesis. Europ. J. Hum. Genet. 13: 336-340, 2005.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

49229 MW

Applications Notes

6

Gene Name Synonym

SRY-box 15

Subcellular Location

Nucleus.

Protein Name

Chromaffin granule amine transporter

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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