Anti-RGS7 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Regulator of G-protein signaling 7 is a protein that in humans is encoded by the RGS7 gene. Enables G-protein beta-subunit binding activity and GTPase activator activity. Involved in positive regulation of GTPase activity. Located in cytosol.

Synonyms

Calretinin; CR; 29 kDa calbindin; CALB2; CAB29

Gene Name

RGS7

Gene ID

6000

UniProt

P49802

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RGS7 recombinant protein (Position: M1-N483) .

Clonality

Polyclonal

Tissue Specificity

Brain.

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunoglobulins, Immunology, Lymphoid, Receptors, Stem Cells

Purification

Immunogen affinity purified.

Form

Liquid

Function

Calretinin is a calcium-binding protein which is abundant in auditory neurons.

References & Citations

1. Gross, M. B. Personal Communication. Baltimore, Md. 4/20/2011. 2. Koelle, M. R., Horvitz, H. R. EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins. Cell 84: 115-125, 1996. 3. Sierra, D. A., Gilbert, D. J., Householder, D., Grishin, N. V., Yu, K., Ukidwe, P., Barker, S. A., He, W., Wensel, T. G., Otero, G., Brown, G., Copeland, N. G., Jenkins, N. A., Wilkie, T. M. Evolution of the regulators of G-protein signaling multigene family in mouse and human. Genomics 79: 177-185, 2002.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

Gene Name Synonym

Calbindin 2

Subcellular Location

Cuticular plate. Cytosol. Nucleus. Synaptic membrane. Dendrite. Gap junction. Neuron projection. Parallel fiber to Purkinje cell synapse. Presynapse. Stereocilium. Synapse.