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Anti-ERGIC1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

This gene encodes a cycling membrane protein which is an endoplasmic reticulum-golgi intermediate compartment (ERGIC) protein which interacts with other members of this protein family to increase their turnover.

Synonyms

Interleukin-17B; IL-17B; Cytokine CX1; Cytokine-like protein ZCYTO7; Neuronal interleukin-17-related factor; Il17b; Nirf, Zcyto7

Gene Name

ERGIC1

Gene ID

57222

UniProt

Q969X5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human ERGIC1 recombinant protein (Position: S42-H290) .

Clonality

Polyclonal

Tissue Specificity

Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Applications

Flow Cytometry

Field of Research

Cytokines, Immunology, Innate Immunity, Interleukins

Purification

Immunogen affinity purified.

Form

Liquid

Function

Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. .

References & Citations

1. Breuza, L., Halbeisen, R., Jeno, P., Otte, S., Barlowe, C., Hong, W., Hauri, H.-P. Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46. J. Biol. Chem. 279: 47242-47253, 2004. 2. Lebenthal, E., Shochet, S. B., Adam, A., Seelenfreund, M., Fried, A., Najenson, T., Sandbank, U., Matoth, Y. Arthrogryposis multiplex congenita--23 cases in an Arab kindred. Pediatrics 46: 891-899, 1970. 3. Reinstein, E., Drasinover, V., Lotan, R., Gal-Tanamy, M., Nachman, I. B., Eyal, E., Jaber, L., Magal, N., Shohat, M. Mutations in ERGIC1 cause arthrogryposis multiplex congenita, neuropathic type. Clin. Genet. 93: 160-163, 2018.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Interleukin 17B

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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