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Anti-RHNO1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Involved in cellular response to radiation; recombinational repair; and regulation of cell cycle process. Located in chromosome and nucleus.

Synonyms

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

Gene Name

RHNO1

Gene ID

83695

UniProt

Q9BSD3

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human RHNO1, which shares 88.2% and 82.4% amino acid (aa) sequence identity with mouse and rat RHNO1, respectively.

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Applications

Flow Cytometry

Field of Research

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Form

Liquid

Function

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

References & Citations

1. Cotta-Ramusino, C., McDonald, E. R., III, Hurov, K., Sowa, M. E., Harper, J. W., Elledge, S. J. A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling. Science 332: 1313-1317, 2011. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 7/11/2011. 3. Kim, J.-W., Fukukawa, C., Ueda, K., Nishidate, T., Katagiri, T., Nakamura, Y. Involvement of C12orf32 overexpression in breast carcinogenesis. Int. J. Oncol. 37: 861-867, 2010.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64099 MW

Applications Notes

6

Gene Name Synonym

RNA-binding protein 47

Subcellular Location

Nucleus .

Protein Name

Follicular dendritic cell secreted peptide

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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