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Anti-IKB epsilon/Nfkbie Antibody Picoband®

Boster Bio Anti-IKB epsilon/Nfkbie Antibody Picoband® catalog # A07073-1. Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon, also known as NFKBIE, is a protein which in humans is encoded by the NFKBIE gene. Predicted to be involved in D-serine transport. Predicted to act upstream of or within negative regulation of transcription, DNA-templated. Predicted to be located in several cellular components, including Golgi apparatus; nuclear lumen; and perinuclear region of cytoplasm. Is expressed in several structures, including central nervous system; dorsal root ganglion; eye; genitourinary system; and thymus. Orthologous to human NFKBIE (NFKB inhibitor epsilon) .

Synonyms

Mimecan; Osteoglycin; Ogn; Og

Gene Name

Nfkbie

Gene ID

18037

UniProt

O54910

Host

Rabbit

Reactivity

Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse IKB epsilon/Nfkbie recombinant protein (Position: Q111-D364) .

Clonality

Polyclonal

Tissue Specificity

Expressed in kidney.

Applications

WB, ELISA

Field of Research

Cell Biology, Cell Cycle, Cell Differentiation, Cytoskeleton/ECM, Extracellular Matrix, Signal Transduction, Structures

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.

References & Citations

1. Hoffmann, A., Levchenko, A., Scott, M. L., Baltimore, D. The I-kappa-B-NF-kappa-B signaling module: temporal control and selective gene activation. Science 298: 1241-1245, 2002. Note: Erratum: Science 318: 1550 only, 2007. 2. Li, Z., Nabel, G. J. A new member of the I-kappa-B protein family, I-kappa-B epsilon, inhibits RelA (p65) -mediated NF-kappa-B transcription. Molec. Cell. Biol. 17: 6184-6190, 1997. 3. Ting, A. Y., Endy, D. Decoding NF-kappa-B signaling. Science 298: 1189-1190, 2002.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

41 kDa

Gene Name Synonym

Osteoglycin

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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